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Article

Lack of association between IFNGR1 gene polymorphisms and biopsy-proven giant cell arteritis.

Clinical and experimental rheumatology - 1 Jan 2000

Torres Orlando, Palomino-Morales Rogelio, Vazquez-Rodriguez Tomas, Castañeda Santos, Morado Immaculada C, Miranda-Filloy Jose A, Amigo-Diaz Encarnacion, Callejas-Rubio Jose L, Fernandez-Gutierrez Benjamin, Martin Javier, Gonzalez-Gay Miguel A

Abstract excerpt

OBJECTIVES: Since IFN-gamma plays a pivotal role in the pathogenesis of giant cell arteritis (GCA), a polygenic primary systemic vasculitis involving elderly people from Western countries, in the present study we analysed for first time the implication of three IFN-gamma receptor (IFNGR) 1 gene variants in the susceptibility to and clinical expression of GCA. METHODS: Two hundred and sixteen biopsy-proven GCA...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20412699

Genes

GCA
IFNGR1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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