Article
Autoimmune disease-associated CD226 gene variants are not involved in giant cell arteritis susceptibility in the Spanish population.
Clinical and experimental rheumatology - 1 Jan 2000
Serrano Aurora, Carmona F David, Miranda-Filloy José A, Castañeda Santos, Rodríguez-Rodríguez Luis, Morado Inmaculada C, Gómez-Vaquero Carmen, Solans Roser, Sopeña Bernardo, Blanco Ricardo, Unzurrunzaga Ainhoa, Ortego-Centeno Norberto, Marí-Alfonso Begoña, de Miguel Eugenio, Hidalgo-Conde Ana, Martín Javier, González-Gay Miguel A
Abstract excerpt
OBJECTIVES: CD226 genetic variants have been associated with a number of autoimmune diseases. The aim of this study was to investigate the potential implication of the CD226 loci in the susceptibility to and main clinical manifestations of giant cell arteritis (GCA). METHODS: A Spanish Caucasian cohort of 455 patients diagnosed with biopsy-proven GCA and 1414 healthy controls were included in the study. Three...
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