Article
Role of rs1343151 IL23R and rs3790567 IL12RB2 polymorphisms in biopsy-proven giant cell arteritis.
The Journal of rheumatology - 1 May 2011
Rodríguez-Rodríguez Luis, Carmona Francisco D, Castañeda Santos, Miranda-Filloy José A, Morado Inmaculada C, Narváez Javier, Marí-Alfonso Beatriz, Gómez-Vaquero Carmen, Amigo-Díaz Encarnación, Ríos-Fernández Raquel, Blanco Ricardo, Llorca Javier, Fernández-Gutiérrez Benjamín, Martín Javier, González-Gay Miguel A
Abstract excerpt
OBJECTIVE: To assess the potential association between the rs1343151 IL23R and the rs3790567 IL12RB2 polymorphisms and giant cell arteritis (GCA). We also studied whether these polymorphisms might influence the phenotypic expression of GCA. METHODS: In total, 357 Spanish patients with biopsy-proven GCA and 574 matched controls were assessed. DNA from patients and controls was obtained from peripheral blood....
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