Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity.

doi:10.1089/rej.2009.0970

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Article

Preliminary evidence of a genetic association between chromosome 9p21.3 and human longevity.

Rejuvenation research - 1 Feb 2010

Emanuele Enzo, Fontana Jacopo M, Minoretti Piercarlo, Geroldi Diego

Abstract excerpt

BACKGROUND: Emerging evidence suggests that there is a significant genetic component to human longevity. One or more genetic variants located on chromosome 9p21.3 and tagged by the single-nucleotide polymorphism (SNP) rs1333049 (G/C) are major risk factors for age-related disorders, including acute myocardial infarction (AMI), stroke, and dementia. We hypothesized that this locus may have widespread effects on...

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PMID: 20230275
DOI: 10.1089/rej.2009.0970

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