Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.

doi:10.1002/ana.21590

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Article

Sequence variants on chromosome 9p21.3 confer risk for atherosclerotic stroke.

Annals of neurology - 1 May 2009

Gschwendtner Andreas, Bevan Steve, Cole John W, Plourde Anna, Matarin Mar, Ross-Adams Helen, Meitinger Thomas, Wichmann Erich, Mitchell Braxton D, Furie Karen, Slowik Agnieszka, Rich Stephen S, Syme Paul D, MacLeod Mary J, Meschia James F, Rosand Jonathan, Kittner Steve J, Markus Hugh S, Müller-Myhsok Bertram, Dichgans Martin

Abstract excerpt

OBJECTIVE: Recent studies have identified a major locus for risk for coronary artery disease and myocardial infarction on chromosome 9p21.3. Stroke, in particular, ischemic stroke caused by atherosclerotic disease, shares common mechanisms with myocardial infarction. We investigated whether the 9p21 region contributes to ischemic stroke risk. METHODS: In an initial screen, 15 single nucleotide polymorphisms...

Topics

Chromosome Mapping
Chromosomes, Human, Pair 9
Coronary Artery Disease
Ethnicity
Europe
Female
Gene Frequency
Genetic Predisposition to Disease
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Male

North America

Odds Ratio

Polymorphism, Single Nucleotide

Risk Assessment

Risk Factors

Stroke

Source

Open in PubMed Open full text

Identifiers

PMID: 19475673
DOI: 10.1002/ana.21590
PMCID: PMC2702695

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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