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Article

The rs1333049 polymorphism on locus 9p21.3 and extreme longevity in Spanish and Japanese cohorts.

Age (Dordrecht, Netherlands) - 1 Apr 2014

Pinós Tomàs, Fuku Noriyuki, Cámara Yolanda, Arai Yasumichi, Abe Yukiko, Rodríguez-Romo Gabriel, Garatachea Nuria, Santos-Lozano Alejandro, Miro-Casas Elisabet, Ruiz-Meana Marisol, Otaegui Imanol, Murakami Haruka, Miyachi Motohiko, Garcia-Dorado David, Hinohara Kunihiko, Andreu Antoni L, Kimura Akinori, Hirose Nobuyoshi, Lucia Alejandro

Abstract excerpt

The rs1333049 (G/C) polymorphism located on chromosome 9p21.3 is a candidate to influence extreme longevity owing to its association with age-related diseases, notably coronary artery disease (CAD). We compared allele/genotype distributions of rs1333049 in cases (centenarians) and controls (younger adults, without (healthy) or with CAD) in two independent cohorts: Spanish (centenarians: n = 152, 128 women,...

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Source

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Identifiers

PMID: 24163049
DOI: 10.1007/s11357-013-9593-0
PMCID: PMC4039251

Genes

CAD

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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