Article
Molecular cloning of a brain-specific, developmentally regulated neuregulin 1 (NRG1) isoform and identification of a functional promoter variant associated with schizophrenia.
The Journal of biological chemistry - 17 Aug 2007
Tan Wei, Wang Yanhong, Gold Bert, Chen Jingshan, Dean Michael, Harrison Paul J, Weinberger Daniel R, Law Amanda J
Abstract excerpt
Neuregulin 1 (NRG1) is essential for the development and function of multiple organ systems, and its dysregulation has been linked to diseases such as cancer and schizophrenia. Recently, altered expression of a novel isoform (type IV) in the brain has been associated with schizophrenia-related ge...
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