Neuregulin 1 and susceptibility to schizophrenia.

doi:10.1086/342734

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Article

Neuregulin 1 and susceptibility to schizophrenia.

American journal of human genetics - 1 Oct 2002

Stefansson Hreinn, Sigurdsson Engilbert, Steinthorsdottir Valgerdur, Bjornsdottir Soley, Sigmundsson Thordur, Ghosh Shyamali, Brynjolfsson Jon, Gunnarsdottir Steinunn, Ivarsson Omar, Chou Thomas T, Hjaltason Omar, Birgisdottir Birgitta, Jonsson Helgi, Gudnadottir Vala G, Gudmundsdottir Elsa, Bjornsson Asgeir, Ingvarsson Brynjolfur, Ingason Andres, Sigfusson Sigmundur, Hardardottir Hronn, Harvey Richard P, Lai Donna, Zhou Mingdong, Brunner Daniela, Mutel Vincent, Gonzalo Acuna, Lemke Greg, Sainz Jesus, Johannesson Gardar, Andresson Thorkell, Gudbjartsson Daniel, Manolescu Andrei, Frigge Michael L, Gurney Mark E, Kong Augustine, Gulcher Jeffrey R, Petursson Hannes, Stefansson Kari

Abstract excerpt

The cause of schizophrenia is unknown, but it has a significant genetic component. Pharmacologic studies, studies of gene expression in man, and studies of mouse mutants suggest involvement of glutamate and dopamine neurotransmitter systems. However, so far, strong association has not been found between schizophrenia and variants of the genes encoding components of these systems. Here, we report the results of a...

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Identifiers

PMID: 12145742
DOI: 10.1086/342734
PMCID: PMC378543

Genes

NRG1

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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