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Article

Age-related changes in the expression of schizophrenia susceptibility genes in the human prefrontal cortex.

Brain structure & function - 1 Sept 2008

Colantuoni Carlo, Hyde Thomas M, Mitkus Shruti, Joseph Andrew, Sartorius Leah, Aguirre Claudia, Creswell Johanna, Johnson Elizabeth, Deep-Soboslay Amy, Herman Mary M, Lipska Barbara K, Weinberger Daniel R, Kleinman Joel E

Abstract excerpt

The molecular basis of complex neuropsychiatric disorders most likely involves many genes. In recent years, specific genetic variations influencing risk for schizophrenia and other neuropsychiatric disorders have been reported. We have used custom DNA microarrays and qPCR to investigate the expression of putative schizophrenia susceptibility genes and related genes of interest in the normal human brain....

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Adaptor Proteins, Signal Transducing
Dopamine and cAMP-Regulated Phosphoprotein 32
Glutamate Decarboxylase
Neuregulin-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Postmortem Changes

Prefrontal Cortex

Receptors, Nerve Growth Factor

Source

Identifiers

PMID: 18470533
DOI: 10.1007/s00429-008-0181-5

Genes

RGS4
ERBB3
FEZ1
GAD1
GRM3
NGFR
NRG1
PRODH

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