Article
Proteome diversification by adenosine to inosine RNA-editing
1 Mar 2010
Abstract excerpt
Nucleotide deamination is a widespread phenomenon frequently leading to a change of the genetic information. Adenosine deaminases that act on RNA (ADARs) convert adenosines to inosines in double-stranded or structured regions of RNAs. Inosines are interpreted as guanosines by most cellular processes and hence, this type of modification can affect the coding potential of an RNA but also its splicing, folding or...
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