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Article

Proteome Diversification by RNA Editing.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2021

Eisenberg Eli

Abstract excerpt

RNA editing is an RNA modification that alters the RNA sequence relative to its genomic blueprint. The most common type of RNA editing is A-to-I editing by double-stranded RNA-specific adenosine deaminase (ADAR) enzymes. Editing of a protein-coding region within the RNA molecule may result in non-synonymous substitutions, leading to a modified protein product. These editing sites, also known as "recoding" sites,...

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PMID: 32729084
DOI: 10.1007/978-1-0716-0787-9_14

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