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Article

Ethanol stabilizes the open state of single 5-hydroxytryptamine(3A)(QDA) receptors.

The Journal of pharmacology and experimental therapeutics - 1 Jun 2010

Feinberg-Zadek Paula L, Davies Paul A

Abstract excerpt

Ethanol enhancement of 5-hydroxytryptamine (5-HT)(3A) receptor-mediated responses may have important consequences in the intoxicating and addictive properties of ethanol. Although the exact mechanism is unknown, ethanol-mediated enhancement of 5-HT(3) receptor current has been proposed to occur due to stabilization of the open-channel state. It has not been possible to directly measure the open state of the...

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Identifiers

PMID: 20200118
DOI: 10.1124/jpet.109.164863
PMCID: PMC2879933

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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