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Article

Characterization of the naturally occurring Arg344His variant of the human 5-HT 3A receptor.

Pharmacological reports : PR - 1 Jan 2000

Combrink Sandra, Kostanian Arevat, Walstab Jutta, Barann Martin, Brüss Michael, Göthert Manfred, Bönisch Heinz

Abstract excerpt

The present study aimed at examining the function and pharmacological properties of the naturally occurring Arg344His variant of the human 5-HT(3A) receptor, identified in a schizophrenic patient. In intact human embryonic kidney (HEK) 293 cells expressing the wild-type (WT) or the variant receptor, the function was analyzed by indirect measurement of agonist-induced Ca(2+) current through the 5-HT(3A) receptor...

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Source

Identifiers

PMID: 19904001
DOI: 10.1016/s1734-1140(09)70134-3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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