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Article

The C and E subunits of the serotonin 5-HT3 receptor subtly modulate electrical properties of the receptor.

Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie - 1 Jan 2018

Yaakob Nor Syafinaz, Nguyen Dan-Thanh, Exintaris Betty, Irving Helen Ruth

Abstract excerpt

Serotonin type 3 (5-hydroxytrptamine-3, 5-HT3) receptors are ligand-gated cation channels present in both central and peripheral nervous systems. In humans there are five different subunits (A, B, C, D and E) of 5-HT3 receptors which can form homomeric or heteromeric receptors that may account for discrepancies in patient responses to treatments. The present study commences characterisation of the profiles of...

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PMID: 29793334
DOI: 10.1016/j.biopha.2017.12.010

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ACE

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