Article
BDNF Val66Met genotype and 6-month remission rates in late-life depression.
The pharmacogenomics journal - 1 Apr 2011
Taylor W D, McQuoid D R, Ashley-Koch A, MacFall J R, Bridgers J, Krishnan R R, Steffens D C
Abstract excerpt
Although not observed in younger adult cohorts, in older individuals the brain-derived neurotrophic factor (BDNF) Val66Met polymorphism is associated with major depressive disorder (MDD) risk. It is further associated with subjective social support and magnetic resonance imaging (MRI) hyperintense lesions, clinical features independently related to MDD. We examined the relationship between this polymorphism and...
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