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Article

Plasma BDNF Level in Major Depression: Biomarker of the Val66Met BDNF Polymorphism and of the Clinical Course in Met Carrier Patients.

Neuropsychobiology - 1 Jan 2017

Colle Romain, Trabado Séverine, David Denis J, Brailly-Tabard Sylvie, Hardy Patrick, Falissard Bruno, Fève Bruno, Becquemont Laurent, Verstuyft Céline, Corruble Emmanuelle

Abstract excerpt

AIMS: Despite the involvement of the brain-derived neurotrophic factor (BDNF) in the physiopathology of major depressive disorder (MDD), the coherence between the components of the BDNF pathway and their link with the clinical features of MDD are insufficiently studied. We aimed to assess in Caucasian depressed patients the impact of the BDNF Val66Met polymorphism on plasma BDNF levels taking into account the...

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Identifiers

PMID: 28848102
DOI: 10.1159/000478862

Genes

BDNF

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