Article
Association of serum BDNF level and Val66Met polymorphism with response to treatment in patients of major depressive disease: A step towards personalized therapy.
Behavioural brain research - 26 Jul 2022
Pathak Piyush, Mehra Aseem, Ram Sant, Pal Arnab, Grover Sandeep
Abstract excerpt
BACKGROUND: Major depressive disorder (MDD) is one of the most common psychiatric disorders and only less than 50% of MDD patients achieve remission after the first antidepressant trial. Hence, it is important to understand the factors associated with response to various antidepressant medications. Brain-derived neurotrophic factor (BDNF) is a member of the neurotrophin family. BDNF and Val66Met polymorphism in...
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