Article
Brain-derived neurotrophic factor Val66Met polymorphism and 6-month antidepressant remission in depressed Caucasian patients.
Journal of affective disorders - 1 Apr 2015
Colle Romain, Gressier Florence, Verstuyft Céline, Deflesselle Eric, Lépine Jean-Pierre, Ferreri Florian, Hardy Patrick, Guilloux Jean-Philippe, Petit Anne-Cécile, Fève Bruno, Falissard Bruno, Becquemont Laurent, Corruble Emmanuelle
Abstract excerpt
BACKGROUND: Whether the Brain Derived Neurotrophic Factor (BDNF) Val66Met polymorphism can predict antidepressant drug efficacy in depressed patients remains unclear, suggesting that it may depend on antidepressant classes. We assessed the impact of Val66Met polymorphism on antidepressant response and remission depending on antidepressant classes. METHODS: In a 6-month prospective, real-world setting, treatment...
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