Article

Activation of the endocytosis pathway stratifies subtypes and therapeutic sensitivity in colorectal cancer

2026-07-05

Abstract excerpt

<title>Abstract</title> <p> Endocytosis regulates receptor trafficking and signaling, yet its role in colorectal cancer (CRC) remains unclear. We analyzed transcriptomic data from 15,025 CRC tumors to evaluate gene expression in clathrin-mediated endocytosis (CME) and the endosomal sorting complexes required for transport (ESCRT) pathway. Pathway-level signatures were compared across consensus molecular subtypes...

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Literature Corpus work: bdbda626-c65c-52f3-8d38-2e8681bea5c7
DOI: 10.21203/rs.3.rs-10164107/v1

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