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Article

A targeted RNAi screen identifies factors affecting diverse stages of receptor-mediated transcytosis.

The Journal of cell biology - 1 Feb 2017

Nelms Bradlee, Dalomba Natasha Furtado, Lencer Wayne

Abstract excerpt

Endosome transport by transcytosis is the primary mechanism by which proteins and other large cargo traverse epithelial barriers in normal tissue. Transcytosis is also essential for establishing and maintaining membrane polarity in epithelia and other polarized cells. To identify novel components of this pathway, we conducted a high-throughput RNA interference screen for factors necessary for the bidirectional...

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Identifiers

PMID: 28069747
DOI: 10.1083/jcb.201609035
PMCID: PMC5294788

Genes

EXOC2
EXOC7
LEPROT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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