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Article

Hierarchical classification strategy for Phenotype extraction from epidermal growth factor receptor endocytosis screening.

BMC bioinformatics - 3 May 2016

Cao Lu, Graauw Marjo de, Yan Kuan, Winkel Leah, Verbeek Fons J

Abstract excerpt

BACKGROUND: Endocytosis is regarded as a mechanism of attenuating the epidermal growth factor receptor (EGFR) signaling and of receptor degradation. There is increasing evidence becoming available showing that breast cancer progression is associated with a defect in EGFR endocytosis. In order to find related Ribonucleic acid (RNA) regulators in this process, high-throughput imaging with fluorescent markers is...

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Source

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Identifiers

PMID: 27142862
DOI: 10.1186/s12859-016-1053-2
PMCID: PMC4855371

Genes

EGFR

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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