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Article

Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats.

Physiological genomics - 1 May 2010

Kim Kyoungmi, Warden Craig H, Griffey Stephen M, Vilches-Moure Jose G, Hansen Susan, Cuppen Edwin, Nijman Isaäc J, Chiu Sally, Stern Judith S

Abstract excerpt

We have previously shown that 90% of outbred obese Zucker Lepr(fa/fa) rats die prematurely of renal disease. Thus, renal disease in obese Zucker Lepr(fa/fa) rats may be caused by the LEPR mutation on chromosome 5, by the obesity, or it may be influenced by Zucker susceptibility alleles of genes o...

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Source

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Identifiers

PMID: 20159938
DOI: 10.1152/physiolgenomics.90367.2008
PMCID: PMC2869106

Genes

LEPR
ACR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20159938-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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