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Article

A molecular genetic method for genotyping fatty (fa/fa) rats.

The American journal of physiology - 1 Jan 1993

Smoller J W, Truett G E, Hirsch J, Leibel R L

Abstract excerpt

After three decades of physiological research, the precise nature of the genetic lesion in Zucker fatty (fa/fa) rats remains unknown. Several methods have been used to identify preobese rats to detect the earliest phenotypic effects of the fa mutation. Most of these methods have used phenotypic characteristics that are not reliable until the second week of life, when increased adiposity is already evident. We...

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Source

Identifiers

PMID: 8094275
DOI: 10.1152/ajpregu.1993.264.1.R8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

A molecular genetic method for genotyping fatty (fa/fa) rats.PMID 8094275Read ↗

Molecular mapping of SSRs for Pgm1 and C8b in the vicinity of the rat fatty locus.Semantic proximity Read ↗

Genetic map of rat chromosome 5 including the fatty (fa) locus.Semantic proximity Read ↗

Utility of a C-jun microsatellite marker in determining gene dosage for fatty (fa).Semantic proximity Read ↗

The rat corpulent (cp) mutation maps to the same interval on (Pgm1-Glut1) rat chromosome 5 as the fatty (fa) mutation.Semantic proximity Read ↗

The Zucker fatty (fa) gene is not a mutation of corticotropin-releasing factor.Semantic proximity Read ↗

Rat obesity gene fatty (fa) maps to chromosome 5: evidence for homology with the mouse gene diabetes (db).Semantic proximity Read ↗

Genetic profiling of two phenotypically distinct outbred rats derived from a colony of the Zucker fatty rats maintained at Tokyo Medical University.Semantic proximity Read ↗

A genome-wide SNP panel for mapping and association studies in the rat.Semantic proximity Read ↗

Use of proton spectroscopy for detection of homozygous fatty ZDF-drt rats before weaning.Semantic proximity Read ↗

Perinatal energy stores and excessive fat deposition in genetically obese (fa/fa) rats.Semantic proximity Read ↗

Codominant effects of the fatty (fa) gene during early development of obesity.Semantic proximity Read ↗

Dietary fat and sex modify heterozygote effects of the rat fatty (fa) allele.Semantic proximity Read ↗

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