Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria.

Journal of the American Society of Nephrology : JASN - 1 Dec 2003

Schulz Angela, Standke Dorothea, Kovacevic Larisa, Mostler Martin, Kossmehl Peter, Stoll Monika, Kreutz Reinhold

Abstract excerpt

The development of renal interstitial fibrosis (RIF) represents an important step in the progression of chronic proteinuric nephropathies. The Munich Wistar Frömter (MWF) rat represents a valuable model to study the progression in proteinuric renal disease. MWF animals demonstrate a significant increase of urinary albumin excretion (UAE) and RIF compared with the spontaneously hypertensive rat (SHR) with low UAE....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Albuminuria
Share to Fibrosis

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Linkage

Share to Kidney

Share to Proteinuria

Share to Rats, Inbred SHR

Share to Rats, Wistar

Source

Identifiers

PMID: 14638907
DOI: 10.1097/01.asn.0000100126.62370.25

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

A major gene locus links early onset albuminuria with renal interstitial fibrosis in the MWF rat with polygenetic albuminuria.PMID 14638907Read ↗

Development of overt proteinuria in the Munich Wistar Frömter rat is suppressed by replacement of chromosome 6 in a consomic rat strain.Semantic proximity Read ↗

Genetic dissection of increased urinary albumin excretion in the munich wistar frömter rat.Semantic proximity Read ↗

Time-course genetic analysis of albuminuria in Dahl salt-sensitive rats on low-salt diet.Semantic proximity Read ↗

Evidence of gene-gene interactions in the genetic susceptibility to renal impairment after unilateral nephrectomy.Semantic proximity Read ↗

Genetic linkage of albuminuria and renal injury in Dahl salt-sensitive rats on a high-salt diet: comparison with spontaneously hypertensive rats.Semantic proximity Read ↗

Genetic analysis of albuminuria in collaborative cross and multiple mouse intercross populationsSemantic proximity Read ↗

Hypertension and albuminuria in chronic kidney disease mapped to a mouse chromosome 11 locus.Semantic proximity Read ↗

Early onset albuminuria in Dahl rats is a polygenetic trait that is independent from salt loading.Semantic proximity Read ↗

Genetic variants on rat chromosome 8 exhibit profound effects on hypertension severity and survival during nitric oxide inhibition in spontaneously hypertensive rats.Semantic proximity Read ↗

Geno-transcriptomic dissection of proteinuria in the uninephrectomized rat uncovers a molecular complexity with sexual dimorphism.Semantic proximity Read ↗

Hypertensive renal disease: susceptibility and resistance in inbred hypertensive rat lines.Semantic proximity Read ↗

Rf-2 Gene Modulates Proteinuria and Albuminuria Independently of Changes in Glomerular Permeability in the Fawn-Hooded Hypertensive RatSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.