Article
Minor gene effect of leptin receptor variant on the body weight in KK/Ta mice.
Diabetes, obesity & metabolism - 1 Sept 2006
Gohda T, Tanimoto M, Kaneko S, Shibata T, Funabiki K, Horikoshi S, Tomino Y
Abstract excerpt
OBJECTIVE: Leptin is an adipocyte-derived hormone involved in body weight regulation that acts through the leptin receptor. Previous studies exploring potential association between the leptin receptor (Lepr) variant and obesity have reported conflicting results. The objectives of the present study are to evaluate (1) whether the Lepr variant contributes to type 2 diabetes and its related disorders such as obesity...
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