Article
Genetic dissection of increased urinary albumin excretion in the munich wistar frömter rat.
Journal of the American Society of Nephrology : JASN - 1 Nov 2002
Schulz Angela, Litfin Andre, Kossmehl Peter, Kreutz Reinhold
Abstract excerpt
An elevated urinary albumin excretion (UAE) is a risk factor for the development of chronic nephropathy and for cardiovascular mortality. The Munich Wistar Frömter (MWF) rat represents a genetic model that develops spontaneously mild hypertension and a 142-fold increased UAE compared with normal Lewis rats at 14 wk of age. The genetic basis of UAE in male MWF was analyzed in relation to BP by using a quantitative...
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