Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats.

American journal of physiology. Renal physiology - 1 Apr 2020

McPherson Kasi C, Shields Corbin A, Poudel Bibek, Johnson Ashley C, Taylor Lateia, Stubbs Cassandra, Nichols Alyssa, Cornelius Denise C, Garrett Michael R, Williams Jan M

Abstract excerpt

The present study examined whether development of renal injury in the nondiabetic obese Dahl salt-sensitive leptin receptor mutant (SSLepRmutant) strain is associated with elevations in glomerular filtration rate and renal lipid accumulation. Baseline mean arterial pressure at 6 wk of age was similar between Dahl salt-sensitive wild-type (SSWT) and SSLepRmutant rats. However, by 18 wk of age, the SSLepRmutant...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to ATP Binding Cassette Transporter 1
Share to CD36 Antigens

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Hemodynamics

Share to Kidney Glomerulus

Share to Proteinuria

Share to Rats, Inbred Dahl

Share to Renal Circulation

Share to Sodium Chloride, Dietary

Source

Open in PubMed Open full text

Identifiers

PMID: 32068459
DOI: 10.1152/ajprenal.00438.2019
PMCID: PMC7191445

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Altered renal hemodynamics is associated with glomerular lipid accumulation in obese Dahl salt-sensitive leptin receptor mutant rats.PMID 32068459Read ↗

Depletion of macrophages slows the early progression of renal injury in obese Dahl salt-sensitive leptin receptor mutant rats.Semantic proximity Read ↗

Diet-induced obesity in C57BL/6J mice causes increased renal lipid accumulation and glomerulosclerosis via a sterol regulatory element-binding protein-1c-dependent pathway.Semantic proximity Read ↗

<i>ALMS1</i> KO rat: a new model of metabolic syndrome with spontaneous hypertensionSemantic proximity Read ↗

Aging and chronic high-fat feeding negatively affect kidney size, function, and gene expression in CTRP1-deficient mice.Semantic proximity Read ↗

Leptin receptor interacts with rat chromosome 1 to regulate renal disease traits.Semantic proximity Read ↗

Genes unlinked to the leptin receptor influence urinary albumin excretion in obese Zucker rats.Semantic proximity Read ↗

Development and characteristics of a new strain of obese hyperinsulinemic and hyperlipidemic Dahl salt-sensitive rat. The Dahl salt-sensitive/NIH-corpulent rat.Semantic proximity Read ↗

Obesity-related kidney disease.Semantic proximity Read ↗

Deep transcriptomic profiling of Dahl salt-sensitive rat kidneys with mutant form of Resp18.Semantic proximity Read ↗

Simultaneous characterization of metabolic, cardiac, vascular and renal phenotypes of lean and obese SHHF rats.Semantic proximity Read ↗

Lipocalin-2 derived from adipose tissue mediates aldosterone-induced renal injury.Semantic proximity Read ↗

Kidney failure, arterial hypertension and left ventricular hypertrophy in rats with loss of function mutation of SOD3.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.