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Article

Genetic variation at selected SNPs in the leptin gene and association of alleles with markers of kidney disease in a Xhosa population of South Africa.

PloS one - 5 Feb 2010

Okpechi Ikechi G, Rayner Brian L, van der Merwe Lize, Mayosi Bongani M, Adeyemo Adebowale, Tiffin Nicki, Ramesar Rajkumar

Abstract excerpt

BACKGROUND: Chronic kidney disease (CKD) is a significant public health problem that leads to end-stage renal disease (ESRD) with as many as 2 million people predicted to need therapy worldwide by 2010. Obesity is a risk factor for CKD and leptin, the obesity hormone, correlates with body fat mas...

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Identifiers

PMID: 20140086
DOI: 10.1371/journal.pone.0009086
PMCID: PMC2816711

Genes

LEP
STS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20140086-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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