Article
Polymorphisms in the non-muscle myosin heavy chain gene (MYH9) are associated with lower glomerular filtration rate in mixed ancestry diabetic subjects from South Africa.
PloS one - 1 Jan 2012
Matsha Tandi Edith, Masconi Katya, Yako Yandiswa Yolanda, Hassan Mogamat Shafick, Macharia Muiriri, Erasmus Rajiv Timothy, Kengne Andre Pascal
Abstract excerpt
OBJECTIVE: Though single nucleotide polymorphisms (SNPs) in the non-muscle myosin gene (MYH9) have been reported to explain most of the excess risk of nondiabetic chronic kidney disease (CKD), in African-Americans, some studies have also shown associations with diabetic end-stage renal disease. We investigated the association of MYH9 SNPs with renal traits in a mixed-ancestry South African population prone to...
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