Article
Potential protective effect of leptin and uncoupling protein-2 genes polymorphism in Egyptian patients with chronic kidney disease.
International urology and nephrology - 1 Nov 2020
Ghazaly Esraa A, El-Saeed Afaf M, Abdelsalam Mostafa, Seoudi Dina M
Abstract excerpt
BACKGROUND: Kidney disease is a serious public health problem worldwide. It is the fifth top-ranking cause of death in Egypt, causing approximately 3.98% of all deaths. This study's objective was to examine whether an association exists between leptin (- 2548G/A) and uncoupling protein-2 45 bp I/D genes, individually and collectively, in CKD and progression to ESRD. METHODS: One hundred patients (69 males, 31...
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