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Article

Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape.

Molecular biology reports - 1 Dec 2023

Pearce Brendon, Jacobs Clifford, Benjeddou Mongi

Abstract excerpt

BACKGROUND: Amphiphilic solute facilitator organic cation transporters mediate the movement of various endogenous and exogenous organic cations, including crucial drugs like metformin, oxaliplatin, and lamivudine. These transporters are now seen as a potential explanation for inter-individual differences in drug effectiveness, contributing to 15-30% of such variability due to genetic factors.The aim of this study...

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Identifiers

PMID: 37924453
DOI: 10.1007/s11033-023-08884-6
PMCID: PMC10676312

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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