Article

Genetic Preservation of SLC22A3 in Local South African Populations

2023-08-23

Abstract excerpt

Organic cation transporters of the amphiphilic solute facilitator family of membrane proteins are involved in the translocation of a diverse range of endogenous and exogenous organic cations. These organic cations include clinically important substrates such as the anti-diabetic drug metformin, the anti-neoplastic drug oxaliplatin, and the anti-retroviral drug lamivudine. Inter-individual variation in drug disposi...

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Literature Corpus work: a1c11e88-25fe-5f83-a4f4-77d193bb25d2
DOI: 10.21203/rs.3.rs-3271771/v1

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