Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Lack of genomic diversity in the SLC47A1 gene within the indigenous Xhosa population.

Drug metabolism and personalized therapy - 1 Jun 2016

Jacobs Clifford, Pearce Brendon, Hoosain Nisreen, Benjeddou Mongi

Abstract excerpt

BACKGROUND: Multidrug and toxin extrusion 1 (MATE1) is an organic cation/H+ exchanger, localized in the apical membrane of proximal renal tubules, which mediates the cellular elimination of organic cations into the renal lumen. These organic cations include clinically important drugs such as metformin, oxaliplatin and cimetidine. Moreover, genetic polymorphisms of SLC47A1, the pharmacogenetically relevant gene...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Gene Frequency
Share to Genomics
Share to Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Organic Cation Transport Proteins

Share to Polymorphism, Single Nucleotide

Share to Population Groups

Share to South Africa

Share to Young Adult

Source

Identifiers

PMID: 27226103
DOI: 10.1515/dmpt-2016-0007

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Lack of genomic diversity in the SLC47A1 gene within the indigenous Xhosa population.PMID 27226103Read ↗

Genetic preservation of SLC22A3 in the Admixed and Xhosa populations living in the Western Cape.Semantic proximity Read ↗

Genetic Preservation of SLC22A3 in Local South African PopulationsSemantic proximity Read ↗

Single nucleotide polymorphisms of the SLC22A2 gene within the Xhosa population of South Africa.Semantic proximity Read ↗

The genetic landscape of the human solute carrier (SLC) transporter superfamilySemantic proximity Read ↗

SLC22A2 - mapping genomic variations within South African indigenous and admixed populations.Semantic proximity Read ↗

Characterization of the genetic profile of CYP2C19 in two South African populations.Semantic proximity Read ↗

Promoter haplotype structure of solute carrier 22 member 2 (SLC22A2) in the Xhosa population of South Africa and their differential effect on gene expression.Semantic proximity Read ↗

Ethnogeographic and inter-individual variability of human ABC transportersSemantic proximity Read ↗

Analysis of pharmacogenetic traits in two distinct South African populations.Semantic proximity Read ↗

Characterization of the genetic variation present in CYP3A4 in three South African populationsSemantic proximity Read ↗

Genetic polymorphisms of the organic cation transporter 1 gene (SLC22A1) within the Cape Admixed population of South Africa.Semantic proximity Read ↗

Genetic variability and population diversity of the human SLCO (OATP) transporter familySemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.