Article
APOL1 genetic variants, chronic kidney diseases and hypertension in mixed ancestry South Africans.
BMC genetics - 26 Jun 2015
Matsha Tandi E, Kengne Andre P, Masconi Katya L, Yako Yandiswa Y, Erasmus Rajiv T
Abstract excerpt
BACKGROUND: The frequencies of apolipoprotein L1 (APOL1) variants and their associations with chronic kidney disease (CKD) vary substantially in populations from Africa. Moreover, available studies have used very small sample sizes to provide reliable estimates of the frequencies of these variants in the general population. We determined the frequency of the two APOL1 risk alleles (G1 and G2) and investigated...
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