Article
Association of cocaine- and amphetamine-related transcript, leptin and leptin receptor gene polymorphisms with anthropometric obesity phenotype indicators in South African learners.
Journal of nutrigenetics and nutrigenomics - 1 Jan 2011
Yako Y Y, Fanampe B L, Hassan M S, Erasmus R T, van der Merwe L, van Rensburg S J, Matsha T E
Abstract excerpt
BACKGROUND/AIMS: Obesity has increased rapidly in South African children and adolescents. Genes involved in appetite regulation have been extensively studied worldwide, but their role in the obesity phenotype in South African Black and mixed-ancestry school adolescents is unknown. METHODS: Seven common polymorphisms in LEP, GHRL, CART and LEPR were analysed for genotype and haplotype association with...
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