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Article

p21 Waf1/Cip1 polymorphisms and risk of esophageal cancer.

Annals of surgical oncology - 1 May 2010

Yang Wenjun, Qi Qi, Zhang Heng, Xu Wenda, Chen Zhiqiang, Wang Li, Wang Yin, Dong Xiaowei, Jiao Haiyan, Huo Zhenghao

Abstract excerpt

BACKGROUND: As the main downstream effecter of tumor suppressor p53, p21(Waf1/Cip1) functions as a unique link from p53 to cell-cycle arrest and DNA repair. In contrast to p53, p21(Waf1/Cip1) has general rare mutations. The natural genetic variants of p21(Waf1/Cip1) have thus emerged for study to enhance understanding of interindividual differences in cancer risk. Two polymorphisms in the p21 ( Waf1/Cip1 ) gene,...

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Share to Carcinoma, Squamous Cell
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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Identifiers

PMID: 20112071
DOI: 10.1245/s10434-009-0882-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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