Article
p21 rs3176352 G>C and p73 rs1801173 C>T polymorphisms are associated with an increased risk of esophageal cancer in a Chinese population.
PloS one - 1 Jan 2014
Zheng Liang, Tang Weifeng, Shi Yijun, Chen Suocheng, Wang Xu, Wang Liming, Shao Aizhong, Ding Guowen, Liu Chao, Liu Ruiping, Yin Jun, Gu Haiyong
Abstract excerpt
OBJECTIVE: Esophageal cancer was the fifth most commonly diagnosed cancer and the fourth leading cause of cancer-related death in China in 2009. Genetic factors might play an important role in esophageal squamous cell carcinoma (ESCC) carcinogenesis. DESIGNS AND METHODS: To evaluate the effect p21, p53, TP53BP1 and p73 single nucleotide polymorphisms (SNPs) on the risk of ESCC, we conducted a hospital based...
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