Article
Association Between p21 Ser31Arg Polymorphism and Gastrointestinal Tract Tumor Risk: A Meta-analysis.
Technology in cancer research & treatment - 1 Oct 2015
Dong Ying, Wang Xiaohua, Ye Xiaofeng, Wang Guanhua, Li Yan, Wang Ningju, Yang Yinxue, Chen Zhiqiang, Yang Wenjun
Abstract excerpt
Human p21 gene is characterized by a polymorphism at codon 31 leading to a Serine-to- Arginine (S/R), two different alleles of p21 Ser31Arg (rs 1801270) polymorphism have been shown to differ significantly in their transcriptional efficiency. More and more investigations are now being carried out to examine a possible link between the p21 Ser31Arg polymorphism and cancer. However, the results were inconclusive....
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