Article
Association between p21 codon 31 polymorphism and esophageal cancer risk in a Taiwanese population.
Cancer letters - 25 Nov 2003
Wu Ming-Tsang, Wu Deng-Chyang, Hsu Hon-Ki, Kao Ein-Long, Yang Chien-Hui, Lee Jang-Ming
Abstract excerpt
P21, which regulates the cell growth cycle, is crucial for normal growth and differentiation. One polymorphism in the p21 codon 31 produces variant proteins with an amino acid change (serine (ser) or arginine (arg)). Although several epidemiologic studies have examined the effect of this polymorphism on cancer risk, the findings remain inconclusive, which has motivated us to evaluate the relationship between p21...
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