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Article

WAF1 genotype and endometrial cancer susceptibility.

Gynecologic oncology - 1 Feb 1999

Hachiya T, Kuriaki Y, Ueoka Y, Nishida J, Kato K, Wake N

Abstract excerpt

The WAF1 protein, which is a downstream mediator of p53, functions as a universal inhibitor of cyclin-dependent kinases. The functional link between p53 and WAF1 suggests the possibility that alteration in WAF1 function constitutes an alternative mechanism to p53 inactivation. However, there are few reports describing somatic mutations of the WAF1 gene in various human malignancies. A polymorphism in the WAF1...

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Source

Identifiers

PMID: 10021299
DOI: 10.1006/gyno.1998.5247

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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