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Article

In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.

The Journal of biological chemistry - 26 Mar 2010

Courtois Elise T, Castillo Claudia G, Seiz Emma G, Ramos Milagros, Bueno Carlos, Liste Isabel, Martínez-Serrano Alberto

Abstract excerpt

Human neural stem cells derived from the ventral mesencephalon (VM) are powerful research tools and candidates for cell therapies in Parkinson disease. Previous studies with VM dopaminergic neuron (DAn) precursors indicated poor growth potential and unstable phenotypical properties. Using the mod...

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Identifiers

PMID: 20106970
DOI: 10.1074/jbc.M109.054312
PMCID: PMC2843236

Genes

NEUROD1
PITX3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20106970-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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