Article

Autologous Versus Allogeneic iPSC-Derived Dopaminergic Neuron Therapy for Parkinson’s Disease: Molecular Mechanisms and Translational Trade-Offs

2026-07-01

Abstract excerpt

Parkinson’s disease is marked by the progressive loss of dopaminergic neurons in the substantia nigra, and current treatments can reduce symptoms but do not stop neurodegeneration. Cell replacement using induced pluripotent stem cell-derived dopaminergic neurons is a promising approach because it directly aims to restore the damaged nigrostriatal pathway. This review focuses on autologous iPSC-derived dopaminergic...

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Literature Corpus work: 5a876f81-2b62-5d6a-9c3d-31c884d9f2ff
DOI: 10.20944/preprints202607.0084.v1

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