Article

Single Cell Gene Expression Analysis Reveals Human Stem Cell-Derived Graft Composition in a Cell Therapy Model of Parkinson’s Disease

2019-08-05

Abstract excerpt

Since the pioneering studies using fetal cell transplants in Parkinson’s disease (PD), brain repair by cell replacement has remained a long-standing and realistic goal for the treatment of neurodegenerative disorders including PD. Authentic and functional midbrain dopamine (DA) neurons can now be generated from human pluripotent stem cells (hPSCs) via a floor plate intermediate 1,2 , and these cell preparations a...

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Literature Corpus work: f59afb67-324f-54fc-80de-ebfaa40a17f2
DOI: 10.1101/720870

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