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Lineage-selective suicide gene system enables post-engraftment editing of cell therapy composition

2026-06-08

Abstract excerpt

<h4>ABSTRACT</h4> Human pluripotent stem cell (hPSC)-derived therapies are advancing rapidly toward clinical application, yet heterogeneity of transplanted cell populations remains a major barrier to safety, predictability and scalability. Existing strategies to mitigate this risk either incompletely eliminate proliferative cells or ablate the entire graft, thereby compromising therapeutic benefit. Here we presen...

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Literature Corpus work
f9771172-b391-5882-b77d-a57a4e468800
DOI
10.64898/2026.06.03.729995
Open publication

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Lineage-selective suicide gene system enables post-engraftment editing of cell therapy compositionDOI 10.64898/2026.06.03.729995
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