Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 1 Dec 2004

Liste Isabel, García-García Elisa, Martínez-Serrano Alberto

Abstract excerpt

Progress in stem cell biology research is enhancing our ability to generate specific neuron types for basic and applied studies and to design new treatments for neurodegenerative diseases. In the case of Parkinson's disease (PD), alternative human dopaminergic (DAergic) neurons other than primary fetal tissue do not yet exist. One possible source could be human neural stem cells (hNSCs), although the yield in...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to bcl-X Protein
Share to Glial Cell Line-Derived Neurotrophic Factor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Graft Survival

Share to Mesencephalon

Share to Nerve Growth Factors

Share to Oxidopamine

Share to Prosencephalon

Share to Tyrosine 3-Monooxygenase

Source

Open in PubMed Open full text

Identifiers

PMID: 15574729
DOI: 10.1523/JNEUROSCI.3208-04.2004
PMCID: PMC6730212

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The generation of dopaminergic neurons by human neural stem cells is enhanced by Bcl-XL, both in vitro and in vivo.PMID 15574729Read ↗

In vitro and in vivo enhanced generation of human A9 dopamine neurons from neural stem cells by Bcl-XL.Semantic proximity Read ↗

Stem-Cell-Based Strategies for the Treatment of Parkinson’s DiseaseSemantic proximity Read ↗

Stem cells for neurodegenerative disorders: where can we go from here?Semantic proximity Read ↗

Parkinson's Disease and Mesenchymal Stem Cells: Potential for Cell-Based TherapySemantic proximity Read ↗

Towards stem cell based therapies for Parkinson's diseaseSemantic proximity Read ↗

Stem cell therapy for Parkinson’s disease: safety and modelingSemantic proximity Read ↗

Dopaminergic neurons from midbrain-specified human embryonic stem cell-derived neural stem cells engrafted in a monkey model of Parkinson's disease.Semantic proximity Read ↗

Stem cell‐based therapy for Parkinson's diseaseSemantic proximity Read ↗

Evaluation of <i>TH</i> -Cre knock-in cell lines for detection and specific targeting of stem cell-derived dopaminergic neuronsSemantic proximity Read ↗

Induced pluripotent stem cells in Parkinson's disease: scientific and clinical challengesSemantic proximity Read ↗

Treatment of Parkinson's disease using cell transplantationSemantic proximity Read ↗

Human Clinical-Grade Parthenogenetic ESC-Derived Dopaminergic Neurons Recover Locomotive Defects of Nonhuman Primate Models of Parkinson's Disease.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.