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Article

Stimulation of TRPC5 cationic channels by low micromolar concentrations of lead ions (Pb2+).

Biochemical and biophysical research communications - 26 Feb 2010

Sukumar Piruthivi, Beech David J

Abstract excerpt

Lead toxicity is long-recognised but continues to be a major public health problem. Its effects are wide-ranging and include induction of hyper-anxiety states. In general it is thought to act by interfering with Ca(2+) signalling but specific targets are not clearly identified. Transient receptor...

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Source

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Identifiers

PMID: 20100462
DOI: 10.1016/j.bbrc.2010.01.074
PMCID: PMC2877782

Genes

TRPC5
TRPM2
TRPM3

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20100462-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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