Article

Versatile Cell and Animal Models for Advanced Investigation of Lead Poisoning

2021-08-25

Abstract excerpt

The heavy metal lead (Pb) can irreversibly damage the human nervous system. To help understand Pb-induced damage, we have developed practical applications for genetically encoded Pb biosensors in cardiac cells and insect central nervous tissue. We applied the optimized fluorescence resonance energy transfer (FRET)-based Pb biosensor Met-lead 1.44 M1 to two living systems to monitor the concentration of Pb: induced...

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Literature Corpus work: 96776fe0-5c66-5ae7-b8b9-8457f6a34354
DOI: 10.20944/preprints202108.0482.v1

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