Article
Clinical features of LRRK2 parkinsonism.
Parkinsonism & related disorders - 1 Dec 2009
Haugarvoll Kristoffer, Wszolek Zbigniew K
Abstract excerpt
Mutations in the leucine-rich repeat kinase 2 (LRRK2) gene were initially identified in large families with autosomal dominant Parkinson disease (PD). These mutations (p.R1441C, p.R1441G, p.Y1699C and p.I2020T) revealed that genetic mutations could cause clinically typical, late-onset PD. Subsequ...
Topics
- Humans
- Leucine-Rich Repeat Serine-Threonine Protein Kinase-2
- Mutation
- Parkinson Disease
- Phosphotransferases
- Protein Serine-Threonine Kinases