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Article

Genetic characteristics of leucine-rich repeat kinase 2 (LRRK2) associated Parkinson's disease.

Parkinsonism & related disorders - 1 Aug 2011

Bardien Soraya, Lesage Suzanne, Brice Alexis, Carr Jonathan

Abstract excerpt

Parkinson's disease (PD) is a common neurodegenerative disorder characterized by the progressive and selective degeneration of nigrostriatal dopaminergic neurons. The discovery of at least six PD-causing genes in predominantly early-onset forms of the disorder has cemented a genetic component to the etiology. Notably, the discovery of mutations in the LRRK2 gene in patients presenting with typical 'sporadic' PD...

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Identifiers

PMID: 21641266
DOI: 10.1016/j.parkreldis.2010.11.008

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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