Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

LRRK2 and Parkinson disease.

Archives of neurology - 1 May 2010

Dächsel Justus C, Farrer Matthew J

Abstract excerpt

OBJECTIVES: To review the molecular genetics and functional biology of leucine-rich repeat kinase 2 (LRRK2) in parkinsonism and to summarize the opportunities and challenges to develop interventions for Parkinson disease (PD) based on this genetic insight. DATA SOURCES: Publications cited are focused on LRRK2 biology between 2004 and March 2009. STUDY SELECTION: Literature selected was based on original...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to Brain Chemistry
Share to Genetic Markers

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Therapy

Share to Leucine-Rich Repeat Serine-Threonine Protein Kinase-2

Share to Parkinson Disease

Share to Protein Serine-Threonine Kinases

Share to Risk Factors

Source

Identifiers

PMID: 20457952
DOI: 10.1001/archneurol.2010.79

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

LRRK2 and Parkinson disease.PMID 20457952Read ↗

Mutations in LRRK2 as a cause of Parkinson's disease.Semantic proximity Read ↗

Leucine-Rich Repeat Kinase 2 in Parkinson’s Disease: Updated from Pathogenesis to Potential Therapeutic TargetSemantic proximity Read ↗

PARK8 LRRK2 parkinsonism.Semantic proximity Read ↗

Leucine‐rich repeat kinase 2 and Parkinson's diseaseSemantic proximity Read ↗

Molecular Pathways Involved in LRRK2-Linked Parkinson's Disease: A Systematic Review.Semantic proximity Read ↗

LRRK2: cause, risk, and mechanism.Semantic proximity Read ↗

Targeting LRRK2 in Parkinson's disease: an update on recent developments.Semantic proximity Read ↗

Role of LRRK2 in physiological activities, diseases, and therapy.Semantic proximity Read ↗

The biology and pathobiology of LRRK2: implications for Parkinson's disease.Semantic proximity Read ↗

Biochemical and molecular features of LRRK2 and its pathophysiological roles in Parkinson's disease.Semantic proximity Read ↗

Exploring LRRK2-dependent Mechanisms in Parkinson's Disease Therapy.Semantic proximity Read ↗

Genetics of Parkinson's disease: LRRK2 on the rise.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.